[Remote] Sr. Bioinformatics Scientist (Assay Development Analytics)

Remote, USA Full-time
Note:The job is a remote job and is open to candidates in USA. Karius is a life science company focused on advancing diagnostic science through microbial insights. The Sr. Bioinformatics Scientist will be a key member of the Assay Development Analytics team, responsible for driving computational aspects of assay development and conducting innovative analyses to enhance diagnostic capabilities for infectious diseases. Responsibilities• Individual contributor to Assay Development Analytics (ADA), which drives the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques.• Participate in experimental design, conduct computational analyses, understand rationale, set the analysis plan, and execute using the necessary tools and methodologies to deliver innovative assays. • Work closely with colleagues across the Molecular Biology and Laboratory Operations teams to understand the properties of the assays and ways to improve our technologies. • Continue to grow and learn in the necessary mathematical, technological, and software aspects of the field through internal knowledge acquisition and staying current with the latest relevant literature.• Open to exploring multiple approaches for problem-solving and modeling including borrowing across a wide range of quantitative disciplines. • Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings. • Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders. • Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share a passion for ensuring the quality of our statistical analysis, via reliability, reproducibility, and rigor. Skills• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master’s degree with 5+ years of directly relevant industry experience. • Publications demonstrating innovative investigation and interpretation of biological data.• Proven proficiency, and understanding of, modern statistics and machine learning. • Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise. • Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams. • Self-starter with the ability to independently drive results and influence project direction. • Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host–environment interactions.• Familiarity with a range of relevant laboratory techniques (either through hands-on work or from collaborations with laboratory-focused colleagues). • Familiarity and experience with bioinformatics tools, approaches, and workflows, particularly those related to next-generation sequencing data analysis. • Familiarity with design of experiments (DOE) approaches to optimize process settings. • Passionate, purpose-driven, and excited about Karius’ mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team. • Detail oriented with exceptional organizational and time management skills. • Self-starting mentality and ability to drive results. • Comfortable working in an environment which combines both research aspects as well as development. • Ability to work effectively and efficiently in a fast-paced (startup) environment. Company Overview• Karius delivers genomic insights into infectious diseases, helping clinicians make critical, life-saving treatment decisions.It was founded in 2014, and is headquartered in Redwood City, California, USA, with a workforce of 51-200 employees. Its website isCompany H1B Sponsorship• Karius has a track record of offering H1B sponsorships, with 1 in 2024, 4 in 2021. Please note that this does not guarantee sponsorship for this specific role. Apply tot his job
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